Most looked-up word in English?

Prag•mat•ic  (prægˈmæt ɪk) adj. 

concerned with practical considerations or consequences; having a practical point of view.

Pragmatic is the most researched word in the 200-year history of Merriam-Webster dictionary. It is currently the 11th most searched for word.
 
Common usage:
  • Doing what works best in the circumstances
  • acting according to practical considerations rather than abstract principles.

Origin - Classical Latin pragmaticus, skilled in business or law; from Classical Greek pragmatikos; from pragma, business, origin, originally a thing done; from prassein, to do.

Obsolete/archaic definitions: 
a. busy; active.
b. officious; meddlesome.
c. dogmatic; opinionated.