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How did The Beatles get their name?

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The their early press interviews The Beatles were repeatedly asked about their name - particularly its unorthodox spelling. They gave many different and often contradictory explanations. This one, given by John Lennon, is particularly implausible.

What is Hanukkah? Why the different spellings?

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Hanukkah is a Jewish religious festival that begins in late November or early December.

Why 'as mad as a hatter'?

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'Mad as a hatter' is usually used to describe extreme eccentricity.  The phrase appears in The Clockmaker (1817) by Thomas Haliburton. Perhaps surprisingly, it is not used directly by Lewis Carroll  in either  Alice in Wonderland ' (1865) or Through the Looking Glass (1871).  Chapter VII of the former is, however, called A Mad Tea Party. It also  attended by a hatter, who the Cheshire Cat calls 'mad. It is the  zany antics at the tea party that are being referenced in modern usage. Mercury poisoning The phrase is commonly believed to allude to the grim effect of mercury poisoning on workers (hatters) manufacturing felt hats.  Mercury poisoning  affects the nervous system, with dementia a common symptom.  Victims developed severe and uncontrollable muscular tremors and twitching limbs, called 'hatter's shakes'; other symptoms included distorted vision and confused speech. Advanced cases developed hallucinations and other psychoti...

Where does the word vaccination come from?

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According to legend, provincial doctor Edward Jenner once overheard a young dairymaid boasting:  “I shall never have smallpox for I have had cowpox."​  This eventually lead to Jenner establishing that smallpox inoculation could provide protection against its far more lethal virological cousin. With a scientist's precision, Jenner called this process 'vaccination' - after vaccinia  the Latin word for cowpox. The cow connection proved great branding - the alleged vanity of the anonymous dairymaid has amused children for two hundred years. It also proved a gift to the original anti-vax movement, who were deeply suspicious of Jenner's devilish new life-saver.  

Where does the word quarantine come from?

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Photo by  CDC  on  Unsplash It is often assumed that the bubonic plague (black death) spread across Europe because the authorities did not understand the concept of contagion. In fact, it was widely understood that an infected person would pass their disease to others. What was not known was the precise transmission mechanism or what you needed to do to avoid contagion. It was obvious, however, that the disease was manifesting itself in particular localities. The key to prevention was isolation. You needed to keeping infected persons out your town, city or community. Who first used the term? In the 1340s the Venetian authorities in charge of the port city of Ragusa (Dubrovnik) issued the first quarantine measures. This was aimed  at ensuring that infected visitors did not mix with the rest of the population.  The edict established an isolation period of trentino giorni (30 days). This applied to anyone arriving from an area known to be affected by bubo...

What is seroprevalence?

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Covid test vial  Photo by  Vincent Ghilione  on  Unsplash Seroprevalence is the level of a pathogen (e.g. the virus Covid-19) found in a particular population - a country, city or region for example. This is measured by administering blood test to as wide a sample of that population as is feasible. Testing The accuracy of seroprevalence is dependent on a number of factors including the size of the sample tested as a proportion of the general population Photo by  Colin D  on  Unsplash the representative nature of that population in terms of age, sex, socio-economic conditions, ethnicity, size of household, number of social interactions, occupation etc. the accuracy of the tests, especially if these are physically difficult to administer. Covid-19 tests are quite physically intrusive as they require a throat swab. the accurate record keeping of the testers the potential for cross-contamination the estimated number of false positiv...